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What is Ranexa?
Ranexa is a prescription medication commonly used to treat the symptoms of ongoing chest pain or discomfort (chronic angina, i.e., pressure that is felt when the heart does not get enough oxygen) that keeps coming back. Angina comes on when extremely little oxygen reaches your heart muscle. Exercise or too much activity causes it. One can use Ranexa alone or with other drugs. You can buy Ranexa online for your chest pain from our reliable pharmacy website. Ranexa belongs to a class of drugs known as Antianginal, Non-nitrates. Ranexa works by improving blood flow to help your heart work more efficiently. Ranexa is not for usage during an acute (or emergency) angina attack.
Ranexa reduces the number of times you may experience chest pain. Relieving symptoms of angina will increase your ability to exercise and perform strenuous work. Ranexa (or Ranolazine) works differently than other medications for angina. Therefore, Ranexa can be used with other medicines for blood pressure control and heart problems. It can be taken with other angina medicines (including nitrates, beta-blockers such as metoprolol, calcium channel blockers such as amlodipine). Ranexa acts by improving how well your heart uses oxygen to do more work with less oxygen.
This medication is usually used with ACE inhibitors, calcium channel blockers, angiotensin receptor blockers, beta-blockers, or nitrates. This drug is generally available only with a doctor’s prescription. Ranexa is available in the following dosage forms- Tablet, Extended Release. It is unknown if Ranexa is safe and effective in children younger than 18 years.
How long does it take for Ranexa to start working?
Ranolazine (or Ranexa) does not work very fast and usually takes around 4 hours for peak effect. The apparent terminal half-life of Ranexa is about 7 hours. A steady-state is generally achieved within three days of twice-daily dosing with Ranexa.
How exactly does Ranexa work?
Ranexa inhibits persistent or late inward sodium current in heart muscle in various voltage-gated sodium channels. Inhibiting that sodium current causes reductions in intracellular calcium levels. This, in turn, causes reduced tension in the heart wall, resulting in reduced oxygen requirements for the muscle.
Ranexa may help control your condition. However, it will not cure it. Continue to take Ranexa even if you feel well. Do not stop taking Ranexa abruptly without talking to the doctor. Don’t use Ranexa for a condition for which it wasn’t prescribed. Don’t give Ranexa to others, even if they have the same condition as yours. It can harm them.
The typical starting Ranexa dose is 500 milligrams orally twice daily. If required, your doctor can increase it to 1000 milligrams orally twice daily. The maximum recommended daily Ranexa dose is 1000 milligrams twice daily. Buy Ranexa online from onlinemedzonline.com because we deliver authentic medicines overnight at your doorstep.
Warning and precautions
Don’t take Ranexa if you take any of the following medications:
- for fungus infection: itraconazole (Sporanox, OnmelTM), ketoconazole (Nizoral)
- for depression: nefazodone
- for infection: clarithromycin (Biaxin)
- for HIV: ritonavir (Norvir), nelfinavir (Viracept), lopinavir and ritonavir (Kaletra), indinavir (Crixivan), saquinavir (Invirase)
- for seizures: phenytoin (Phenytek, Dilantin, Dilantin125), phenobarbital, carbamazepine (Tegretol)
- for tuberculosis (TB): rifabutin (Mycobutin), rifampin (Rifadin), rifapentine
- St. John’s wort (Hypericum perforatum)
- medications for your heart
- for cholesterol
- for diabetes
- for transplant
- for nausea and vomiting
- for mental problems
- you have scarring (cirrhosis) on your liver
Before you take Ranexa, tell the doctor if you:
- Have a family history of a heart condition known as ‘QT prolongation or long QT syndrome.’
- Have or have ever had an abnormal electrocardiogram (ECG: a test that measures the electrical activity of your heart) or low levels of potassium in the blood
- Have liver problems
- Are allergic to Ranolazine, any other drugs, or any of the ingredients in Ranexa ER tablets.
- Have kidney problems
- Are planning a pregnancy, it isn’t known if Ranexa can harm your unborn baby.
- Plan to breastfeed or are breastfeeding. Ranexa may pass into your breast milk. You and the doctor should decide if you should breastfeed.
Tell the doctor about all the medicines you take, including nonprescription and prescription drugs, vitamins, and herbal supplements. Ranexa can affect how other drugs work, and other medications may affect how Ranexa works.
How should I take Ranexa?
Take Ranexa precisely as the doctor tells you. Your doctor will tell you how much Ranexa to take and when to take it. Ranexa comes as an ER (long-acting) tablet to take by mouth. Ranexa is usually taken without or with food twice daily. Take Ranexa at around the same time each day. Follow the directions on your prescription label carefully, and ask the doctor to explain any part you do not understand. Don’t take less or more of it or take the drug more often than prescribed by the doctor. Swallow the Ranexa tablets whole; do not chew, break, or crush them before swallowing.
The doctor shall start you on a low dosage of Ranexa and gradually increase your dosage of Ranexa. Do not take Ranexa to treat a sudden attack of angina. The doctor will tell you what you must do if you experience an episode of angina. Ensure that you understand these directions. Do not change your Ranexa dose unless your doctor tells you to. Tell the doctor if you still experience symptoms of angina after starting Ranexa. Use this medicine regularly to get the most benefit from it. Ask the pharmacist for a copy of the manufacturer’s information for the patient.
If you forget to take a dose of Ranexa, wait to take the next Ranexa dose at your regular time. Don’t make up for the missed dose. Don’t take more than one Ranexa dose at a time. If you take too much Ranexa, call the doctor or immediately go to the nearest emergency room.
What are the inactive and active ingredients in Ranexa?
Active ingredient: Ranolazine
Inactive ingredients: 500 mg Ranexa tablet: carnauba wax, methacrylic acid copolymer (Type C), hypromellose, magnesium stearate, microcrystalline cellulose, polyvinyl alcohol, talc, polyethylene glycol, sodium hydroxide, titanium dioxide, Iron Oxide Yellow, and Iron Oxide Red
1000 mg tablet: carnauba wax, hypromellose, methacrylic acid copolymer (Type C), magnesium stearate, microcrystalline cellulose, sodium hydroxide, titanium dioxide, polyethylene glycol, lactose monohydrate, triacetin, and Iron Oxide Yellow
Side effects of Ranexa
Ranexa can cause severe side effects, such as:
- Changes in the electrical activity of your heart, known as QT prolongation- Your doctor can check the electrical activity of your heart with an ECG. Tell the doctor immediately if you feel lightheaded, faint, or irregular or fast heartbeat while taking Ranexa. These can be symptoms related to QT prolongation.
- Kidney failure in people with severe kidney problems- Your doctor will need to do tests to check how your kidneys are working.
- fast or pounding heartbeats,
- fluttering in your chest,
- painful or difficult urination,
- little or no urination,
- swelling in your feet or ankles,
- shortness of breath, and
- feeling tired
The more common side effects of Ranexa include headache, nausea, constipation, and dizziness. Call the doctor for medical advice regarding side effects.